MK-677 is a drug that works by activating the ghrelin receptor in the body. It increases the natural production of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), both of which are important for growth and repair in the body, without raising cortisol (a stress hormone). Researchers are studying MK-677 for its potential to treat conditions like growth hormone deficiency, muscle and bone loss, loss of appetite, and Alzheimer’s disease. In studies with mice, it showed potential to prevent Alzheimer’s disease when given before significant buildup of harmful proteins in the brain. Additionally, research suggests that MK-677 could greatly improve sleep quality.